Detailed Product Description
| CAS:: |
120511-73-1 |
Assay:: |
99% |
| High Light: |
clomifene citrate, estradiol benzoate |
Raw Powder Anastrozole Arimidex Anti-estrogen Inhibit Side Effect
Tag:Hormone,Anastrozole,Arimidex,Steroid,Antineoplastic,Anastrazole,AstraZeneca
Product Name | Anastrozole |
Synonym | Arimidex,Anastrazole,AstraZeneca |
CAS | 120511-73-1 |
MF | C17H19N5 |
MW | 293.37 |
Molecular Structure | 
|
Assay | 99% |
Quality Standards | USP |
Appearance | White to white crystalline powder |
Package | 1kg/Foil bag |
Place of Origin | China |
Brand Name | SMQ |
Certification | ISO9001, ISO14000, KOSHER |
Model Number | 120511-73-1 |
MOQ | 10g |
Ref. Price | USD 9.18/g |
Packaging Details | 1kg/bag,100grams/bag, 10grams/bag |
Delivery Time | 1-3 days |
Payment Terms | T/T, Western union, Money gram |
Supply Ability | 100KGS/week |
1. OverView:
Anastrozole is a non-steroidal aromatase-inhibiting drug approved for treatment of breast cancer after surgery, as well as for metastasis in both pre and post-menopausal women. The severity of breast cancer can be increased by estrogen, as sex hormones cause hyperplasia, and differentiation at estrogen receptor sites. Anastrozole works by inhibiting the synthesis of estrogen.
2. Description:
Anastrozole is used to treat certain types of breast cancer in women who have already stopped menstruating (postmenopausal). It is also used for women who have already had other cancer treatments (e.g., tamoxifen).
Many breast cancer tumors grow in response to estrogen. This medicine interferes with the production of estrogen in the body. As a result, the amount of estrogen that the tumor is exposed to is reduced, limiting the growth of the tumor.
3. Why is this medication prescribed:
Anastrozole is used with other treatments, such as surgery or radiation, to treat early breast cancer in women who have experienced menopause (change of life; end of monthly menstrual periods). This medication is also used in women, who have experienced menopause, as a first treatment of breast cancer that has spread within the breast or to other areas of the body. This medication is also used to treat breast cancer in women whose breast cancer has worsened after taking tamoxifen (Nolvadex). Anastrozole is in a class of medications called nonsteroidal aromatase inhibitors. It works by decreasing the amount of estrogen the body makes. This can slow or stop the growth of many types of breast cancer cells that need estrogen to grow.
4. Recommended Dose:
1. Usage in men:
Anastrozole has been tested for reducing estrogens, including estradiol, in men. Excess estradiol in men can cause benign prostatic hyperplasia, gynecomastia, and symptoms of hypogonadism. It can also contribute to increased risk of stroke, heart attack, chronic inflammation, prostate enlargement and prostate cancer. Some athletes and body builders use anastrozole as part of their steroid cycle to reduce and prevent symptoms of excess estrogen--gynecomastia, emotional lability and water retention. Study data suggests dosages of 0.5 mg to 1 mg a day reduce serum estradiol approx. 50% in men, which differs in postmenopausal women.
2. Usage in children:
Anastrozole may be used off-label in children with precocious puberty, or children with pubertal gynecomastia.Following the onset of puberty, the epiphyseal plate begins to close due to an increased amount of estrogen production escaping local metabolism and spreading to the circulatory system. It is shown to help slow this process, and increase adult height prediction in adolescent males treated with protein-based peptide hormones for the treatment of growth hormone deficiency.
ANALYSIS | SPECIFICATIONS | RESULTS |
ASSAY | 98.0%--102.0% | 99.7% |
CHEMICAL CONTROL |
IDENTIFICATION | IR
HPLC
reactive | Conform with standard IR
Conform with standard HPLC
Conform |
SOLUBILITY | Freely soluble in methanol,acetone,ethanol and tetrahydrofuran. And very soluble in acetonitrile | Complies |
MELTING POINT | 81.0 ~ 84.0℃ | 82.9 ~ 83.3℃ |
TOTAL IMPURIRY | 0.5%(max) | 0.20% |
Total unspecified impurity | 0.2%(max) | 0.11% |
Individual unspecified impurity | 0.1%(max) | 0.07% |
Related compound B | 0.2%(max) | 0.05% |
Related compound C | 0.2%(max) | 0.02% |
Related compound D | 0.1%(max) | 0.06% |
Related compound E | 0.1%(max) | 0.08% |
LIMIT OF CYCLOHEXANE | 0.08%(max) | ND |
LIMIT OF ETHYLACETATE | 0.1%(max) | 0.05% |
PHYSICAL CONTROL |
DESCRIPTION | White crystalline powder | Complies |
WATER | 0.3%(max) | 0.25% |
HEAVY METAL | 0.001%(max) | Complies |
RESIDUE ON IGNITION | 0.1%(max) | 0.06% |
STORAGE | Cool and dry |
SHELF LIFE | 24 months |
Our advantages:
1. High quality products with competitive prices.
2. We provide professional service.
3. Enough stock and Fast delivery.
4. We asure safe and effective shipping method.
5. Fast response to any emails or problems.
Available tracking numbers to USA:
EE689150169CN
EE689150084CN
EE750056148CN
EE689151059CN
EA211716874HK
