Detailed Product Description
| Alias: |
Cytomel T3 |
CAS No: |
55-06-1 |
| Einecs No: |
200-223-5 |
MF: |
C15H11I3NNaO4 |
| MW: |
672.96 |
Purity: |
98.0% |
| Appearance: |
White Or Light Yellow Powder |
|
|
| High Light: |
fat cutting steroids, fat loss steroids |
White liothyronine Sodium T3 Cytomel powder for weight loss
Quick Detail:
Liothyronine sodium
Alias: Cytomel T3;
CAS No: 55-06-1
Einecs No: 200-223-5
MF: C15H11I3NNaO4
MW: 672.96
Purity: 98.0%
Appearance: White or light yellow powder, almost tasteless.
Description:
Liothyronine sodium is a synthetic (man-made) version of one of the two hormones made by the thyroid gland, triiodothyronine. It is used for treating individuals who are hypothyroid (do not produce enough thyroid hormones). Thyroid hormones increase the metabolism (activity) of all cells in the body. In the fetus, newborn infant and child, thyroid hormones promote growth and development of tissues. In adults, thyroid hormones help to maintain the function of the brain, the use of food by the body, and body temperature. The FDA approved liothyronine in May 1956.
Liothyronine is the most potent form of thyroid hormone. As a salt of triiodothyronine (T3), it is chemically similar and pharmacologically equivalent to T3. As such, it acts on the body to increase the basal metabolic rate, affect protein synthesis and increase the body's sensitivity to catecholamines by permissiveness.
Thyroid hormone drugs are natural or synthetic preparations containing tetraiodothyronine (T4, levothyroxine) sodium or triiodothyronine (T3, liothyronine) sodium or both. T4 and T3 are produced in the human thyroid gland by the iodination and coupling of the amino acid tyrosine. T4 contains four iodine atoms and is formed by the coupling of two molecules of diiodotyrosine (DIT).
Applications:
Liothyronine is used to treat hypothyroidism (low production of thyroid hormone) in adults and children. Prolonged hypothyroidism can result in a condition called myxedema in which patients develop swollen lips, thickened nose, and unusual deposits of material in the skin that are dry and waxy. These deposits also may appear in body tissues other than the skin. Liothyronine also is used for suppressing production of thyroid stimulating hormone in patients with goiters and for testing how well the thyroid gland is functioning.
Cytomel (liothyronine sodium) is used to treat hypothyroidism (low thyroid hormone). It is also used to treat or prevent goiter (enlarged thyroid gland), and is also given as part of a medical tests for thyroid disorders. Cytomel is a synthetic thyroid hormone. This medication is available in generic form. Common side effects include nausea. In rare cases, temporary hair loss may occur during the first few months of starting this drug (especially in children).
Specifications:
| tem |
Specification |
Result |
| Appearance |
An odorless, almost white or buff colored powder |
pass |
| Solubility |
1,Very slightly soluble in water |
pass |
| 2,slightly soluble in alcohol |
pass |
| 3,practically insoluble in most other organic solvents |
pass |
| 4,disolves in diluted aqueous sodium hydroxide solutions |
Pass |
| Identification |
a) Heat about 50 mg with a few drops of sulfuric acid in a porcelain crucible: violet vapors of iodine are evolved. |
pass |
| b)The retention time of the major peak is confirm to the RS |
pass |
| Loss on Drying |
Not more than 4.0% |
0.46% |
|
[a]20/D
C=1 in 1M HCl/EtOH 1:4
|
+18 ~ +22o |
＋20.9o |
| Assay(HPLC) |
Not less than 95.0% |
99.18% |
| Levothyroxine sodium |
Not more than 5.0% |
0.68% |
| Conclusion: |
Up to the Standard for Export |
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