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safe Dextromethorphan Hydrobromide DXM Weight Loss Steroids Medical Product

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safe Dextromethorphan Hydrobromide DXM Weight Loss Steroids Medical Product

Large Image :  safe Dextromethorphan Hydrobromide DXM Weight Loss Steroids Medical Product

Product Details:

Place of Origin:China
Certification:ISO9001; ISO14000

Payment & Shipping Terms:

Minimum Order Quantity:1kg
Price:USD575/kg
Packaging Details:100g/bag, 500g/bag, 1kg/bag
Delivery Time:1-3 work days
Payment Terms:T/T, Western Union, MoneyGram
Supply Ability:100kg/month
Detailed Product Description
CAS:: 125-69-9 Assay:: 99%
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Pharma Grade 99% Min Dextromethorphan Hydrobromide DXM Weight Loss Drug

 

Basic Description:

 

Dextromethorphan (DXM or DM) is an antitussive (cough suppressant) drug. It is one of the active ingredients in many over-the-counter cold and cough medicines, including generic labels and store brands, Benylin DM, Mucinex DM, Robitussin, NyQuil, Dimetapp, Vicks, Coricidin, Delsym, TheraFlu, and others. Dextromethorphan has also found other uses in medicine, ranging from pain relief to psychological applications. It is sold in syrup, tablet, spray, and lozenge forms. In its pure form, dextromethorphan occurs as a white powder.

 

DXM is also used recreationally. When exceeding label-specified maximum dosages, dextromethorphan acts as a dissociative hallucinogen. Its mechanism of action is via multiple effects, including actions as a nonselective serotonin reuptake inhibitor and a sigma-1 receptor agonist.DXM and its major metabolite, dextrorphan, also acts as an NMDA receptor antagonist at high doses, which produces effects similar to, yet distinct from, the dissociative states created by other dissociative anaesthetics such as ketamine and phencyclidine. As well, the metabolite 3-methoxymorphinan of dextrorphan (thus a second-level metabolite of DXM) produces local anesthetic effects in rats with potency above dextrorphan, but below that of DXM.

 

Medical use

 

Generic Dextromethorphan syrup.

The primary use of dextromethorphan is as a cough suppressant, for the temporary relief of cough caused by minor throat and bronchial irritation (such as commonly accompanies the flu and common cold), as well as those resulting from inhaled particle irritants.

 

A 2004 study showed that dextromethorphan was no more effective for children than a placebo.Studies conducted by the American Academy of Pediatrics show that dextromethorphan is not superior to a placebo in providing nocturnal symptom relief for children with cough and sleep difficulty due to upper respiratory infections.

 

A combination of dextromethorphan and quinidine, a CYP2D6 inhibitor, has been shown to alleviate symptoms of easy laughing and crying (pseudobulbar affect) in patients with amyotrophic lateral sclerosis and multiple sclerosis.Dextromethorphan is also being investigated as a possible treatment for neuropathic pain and pain associated with fibromyalgia.In 2010, the FDA approved the combination product dextromethorphan/quinidine (Nuedexta) for the treatment of pseudobulbar affect (PBA).

 

Dextromethorphan has been shown to be effective in treating opioid withdrawal. At doses of 2 mg/kg in rats all signs of opioid withdrawal were eliminated.

 

Tag:Dextromethorphan HydrobromideWeight Loss Powders;Dextromethorphan Maleate HBR;Antitussive Drug

 

Product Name

Dextromethorphan Hydrobromide

Synonyms

Dextromethorphan maleate HBR; dextromethorphan HBR; (9alpha,13alpha,14alpha)-3-methoxy-17-methylmorphinan hydrobromide; 3-methoxy-17-methylmorphinan hydrobromide; (9alpha,13alpha,14alpha)-3-methoxy-17-methylmorphinan hydrobromide hydrate; Destromethorphan hydrobromide

Molecular Formula

C18H28BrNO2

Molecular Weight

370.3244

InChI

InChI=1/C18H25NO.BrH.H2O/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18;;/h6-7,12,15,17H,3-5,8-11H2,1-2H3;1H;1H2/t15-,17+,18+;;/m1../s1

CAS Registry Number

125-69-9

EINECS

204-750-1

Molecular Structure

safe Dextromethorphan Hydrobromide DXM Weight Loss Steroids Medical Product

Boiling point

486.1°C at 760 mmHg

Flash point

247.8°C

Vapour Pressure

2.92E-10mmHg at 25°C

Assay

99%

Appearance

White or white crystalline powder

 

 


TEST

 

SPECIFICATION

 

TEST RESULT

01

  

Apperance

 

 

Practically white crystal or crystalline powder

 

White crystalline powder

02

 

 

Identification

A. FT-IR

 

The sample spectrum correspond to that of the reference standard

 

Conforms

B. UV

 

Not more than 3.0% difference of RS(on anhydrous basis)

 

  1.4%

C. Bromide Test

       

Yellow white precipitate formed

 

 Conforms

03

 

Specific rotation A

 

1.8w/v in water:Not more than 1.0%difference of RS

At 325nm and 25℃(on anhydrous basis)

 

 0.23%

04

 

Specific rotation B

 

2.0%w/v in 0.1M HCL: +28℃to +30℃ at 589nm and 20℃(on anhydrous basis)

 

+28.2℃

05

 

Clarity of solution

 

5.0%w/v in alcohol:Clear and colorless

 

Conforms

06

 

 

PH

 

5.2-6.5(1 in 100 water solution)

 

6.1

07

 

Acidity or Alkalinity

 

Not more than 0.4ml of 0.01M HCLconsumed

 

0.24ml

08

 

Water(by KF Titration)

     

4.0%—5.5%

 

5.0%

 

09

 

Relates substances

(by HPLC;ph;Eur)

 

 

a)For each of impurities A,B,C,D not more than 0.5%

 

Impurities A,B,C,D; Not detected.

 

 

b)Among impurities A,B,C,D not more than one greater than 0.25%

 

0

 

C)For each of unspecified impurities,not more than0.10%

 

 ﹤0.05%

 

d)Total impurities not more than 1.0%

 

  ﹤0.05%

10

 

Residue on Ignition

  

   Not  more  than 1.0%

 

 0.05%

11

 

N,N-Dimethylaniline

    

    Not more than 0.001%

 

Conforms

12

 

Phenolic compounds

 

 

No blue-green color develops

 

Conforms

13

 

Assay A (by HPLC)

  

98.0%~102.0%(on anhydrous basis)

100.0%

14

 

Assay B(by titration)

 

99.0%~101.0%(on anhydrous basis)

 

100.4%

15

 

Residual solvents

        Methanol≤3000ppm

 

        Toluene≤890ppm

 

        Acetone≤5000ppm

 52ppm

 

 0.8ppm

 

 2ppm

16

 

Storage

       

 

 Preserve in tight containers;protected from light

 

 

Conforms

 

Our advantages:

1. High quality products with competitive prices.

2. We provide professional service.

3. Enough stock and Fast delivery.

4. We asure safe and effective shipping method.

5. Fast response to any emails or problems.

 

Available tracking numbers to USA:

EE689150169CN

EE689150084CN

EE750056148CN

EE689151059CN

EA211716874HK

 

Contact Details
Huaju Biotechnology Co.,Ltd

Contact Person: Mr. Eric

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