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HomeProductsProgesterone Hormones

Oral contraceptive Dienogestrel Progesterone Hormones Powder 65928-58-7

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Oral contraceptive Dienogestrel Progesterone Hormones Powder 65928-58-7

Large Image :  Oral contraceptive Dienogestrel Progesterone Hormones Powder 65928-58-7

Product Details:

Place of Origin:China
Certification:ISO9001; ISO14000

Payment & Shipping Terms:

Minimum Order Quantity:100g
Price:USD2392/100g
Packaging Details:100g/bag, 500g/bag, 1kg/bag
Delivery Time:1-3 work days
Payment Terms:T/T, Western Union, MoneyGram
Supply Ability:100kg/month
Detailed Product Description
CAS:: 65928-58-7 Assay:: 98%
High Light:

megestrol acetate

,

chlormadinone acetate

 

Oral contraceptive Dienogestrel Progesterone Hormones Powder 65928-58-7

 

Quick Detail:

 

Product name

Dienogestrel

Other name

Dienogest; Endometrion; STS 557; Visanne ect

CAS register number

65928-58-7

Molecular formula

C20H25NO2

Molecular weight

311.42

Appearance

White crystalline powder

Molecular structure

Oral contraceptive Dienogestrel Progesterone Hormones Powder 65928-58-7

Assay

98%min

Usage

Dienogest newly developed contraceptive drug, due to its strong inhibition of ovulation and used oral contraceptives

 

 Description:

Dienogest was synthesised in 1979 in Jena, Germany under the leadership of Prof. Kurt Ponsold, was initially referred to as STS 557. It was found that its potency was 10 times that of levonorgestrel. The first product on the market to contain dienogest as a contraceptive pill Valette in 1995 made by Jenapharm. It has been little used outside of Germany.

Dienogest is an orally-active semisynthetic, steroidal progestogen (or progestin). It is available for use as an oralcontraceptive in combination with ethinylestradiol. It has antiandrogenic activity and as a result can improve androgenicsymptoms. It is a non-ethinylated progestin which is structurally related to testosterone. Dienogest given in isolation is available for the treatment of endometriosis under the trade name Visanne.

 

Usage:

Dienogest is used primarily as a contraceptive in combination with ethinylestradiol. It is given as a tablet containing 2 mg of dienogest and 30 μg of ethinylestradiol. Dienogest is also available in a quadriphasic oral contraceptive pill combined with estradiol valerate, marketed as Natazia in the United States and Qlaira in some European countries. This formulation is also approved for the treatment of heavy menstrual bleeding.

The minimum dose required to inhibit ovulation has been found to be approximately 1 mg.

 

How does it work?

1. Dienogest has moderate affinity for the progesterone receptor in human uterus tissue, in vitro, about 10% that of progesterone.

2. Inhibition of ovulation

The minimum effective dose of oral dienogest required to inhibit ovulation is 1 mg/day. The inhibition of ovulation by dienogest occurs mainly via peripheral action as opposed to central action on gonadotrophin secretion. Oral treatment of dienogest 2 mg/day in cyclical women reduced serum progesterone levels to anovulatory levels, however serum levels of lutenising hormone and follicle-stimulating hormone are not significantly altered.

 

Adverse effects:

Adverse effects associated with dienogest are the same as those expected of a progestogen. These include weight gain, increased blood pressure, breast tenderness and nausea. It produces no androgenic side effects and has little effect on metabolic and lipid haemostatic parameters.

 

                      

TEST

SPECIFICATIONS

RESULTS

Appearance

White to pale yellow crystalline powder

Conforms

Melting point

210°C-218°C

212°C-216°C

Clarity and Color of Solution

Conforms

Conforms

Specific Rotation

-338°~-358°

-351.1°

Total  impurity

≤1.0%

0.08%

Max single impurity

≤0.1%

0.04%

Loss on drying

≤1.0%

0.10%

Residue on Ignition

≤0.1%

0.045%

Heavy Metal

≤10ppm

Conforms

Assay 

≥98.0 

98.6%

Conclusion: Conforms to the Enterprise Standards.

 

 

Our advantages:

1. High quality products with competitive prices.

2. We provide professional service.

3. Enough stock and Fast delivery.

4. We asure safe and effective shipping method.

5. Fast response to any emails or problems.

 

Available tracking numbers to USA:

EE689150169CN

EE689150084CN

EE750056148CN

EE689151059CN

EA211716874HK

 

 

3.

Place of Origin:

China

Brand Name:

NANJIAN

Certification:

ISO9001, ISO14000, KOSHER

Model Number:

65928-58-7

 

4.

Minimum Order Quantity:

10 grams

Price:

negotiation

Packaging Details:

1kg/bag,100grams/bag, 10grams/bag

Delivery Time:

1-3 days

Payment Terms:

T/T, Western union, Money gram

Supply Ability:

100KGS/week

Contact Details
Huaju Biotechnology Co.,Ltd

Contact Person: Mr. Eric

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