Detailed Product Description
| High Light: |
hair growth steroid, finasteride powder |
98319-26-7 Hair Growth Powder Finasteride Propecia Treat Hair Loss
Quick Detail:
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Product Name
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Finasteride
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CAS Registry Number
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98319-26-7
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Molecular Formula
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C23H36N2O2
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Molecular Weight
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372.5441
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InChI:
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InChI=1/C23H36N2O2/c1-21(2,3)25-20(27)17-8-7-15-14-6-9-18-23(5,13-11-19(26)24-18)16(14)10-12-22(15,17)4/h11,13-18H,6-10,12H2,1-5H3,(H,24,26)(H,25,27)/t14-,15-,16-,17+,18?,22-,23+/m0/s1
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Assays:
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99%
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Appearance:
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White or almost white crystalline solid
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Use:
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Used to treat man conditions such as prostatic hypertrophy and bald
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Finasteride Profile:
Finasteride (MK-906, Proscar and Propecia by Merck, among othergeneric names) is a synthetic drug for the treatment of benign prostatic hyperplasia (BPH) and male pattern baldness (MPB). It is a type II 5α-reductase inhibitor. 5α-reductase is an enzyme that converts testosteroneto dihydrotestosterone (DHT).
Medical uses:
Benign prostatic hyperplasia
Physicians use finasteride for the treatment of benign prostatic hyperplasia (BPH), informally known as an enlarged prostate. The FDA-approved dose is 5 mg once a day. Six months or more of treatment with finasteride may be required to determine the therapeutic results of treatment. If the drug is discontinued, any therapeutic benefits reverse within about 6–8 months. Finasteride may improve the symptoms associated with BPH such as difficulty urinating, getting up during the night to urinate, hesitation at the start of urination, and decreased urinary flow.
Male pattern baldness
Three Phase 3 clinical trials examined the efficacy of finasteride in the treatment of mild to moderate male pattern baldness. The primary endpoints of each trial were hair count and user self-assessment. Secondary endpoints included investigator assessment and examination of scalp photographs. Each patient also filled out questionairres regarding sexual health and non-scalp body hair growth. These trials enrolled 1879 men and had a duration of one year. Of these 1879 men, 1215 elected to participate in a one year double blind extension trial. Additional extension trials were performed such that 323 men experienced over 4 years of treatment.
Across all three trials, at one year men taking Propecia had 107 more hairs per 1 inch diameter section of scalp (in the area affected by hair loss) than men treated with placebo. At two years the difference was 138 hairs. Maximum hair gain occurred during the first two years, but because hair loss was more rapid in the placebo treated group, the difference between treated and placebo groups increased to 277 hairs per inch circle at 5 years. Self assessment showed that treated patients perceived an improvement in hair density and overall appearance. These results were supported by investigator ratings and by independent readers examining scalp photographs.
At the end of the first year, the sexual health questionaire revealed differences in sexual interest, erections, and perception of sexual problems that favored the placebo group. However, no significant difference was seen in the question on overall satisfaction with sex life.
Off-label uses
Finasteride is sometimes used in hormone replacement therapy for male-to-female transsexuals in combination with a form of estrogen due to its antiandrogen properties.[5][6] However, little clinical research of finasteride use for this purpose has been conducted and evidence of efficacy is limited. Indeed, finasteride is a substantially weaker antiandrogen in comparison to conventional antiandrogens like spironolactone and cyproterone acetate.
Specificatioin:
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Test Items
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Specification
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Test Results
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Description
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White or off-white crystalline powder
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Off-white crystalline powder
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Specific rotation
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-56°~-60°
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-58.2°
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Identification
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IR
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Matches with working standard
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Complies
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HPLC
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Solubility
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Freely soluble in chloroform and in alcohol; Very slightly soluble in water
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Conform
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Heavy metals
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≤10ppm
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＜10ppm
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Water
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≤0.3%
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0.22%
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Residue on ignition
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≤0.1%
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0.05%
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Relative material
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Maximum impurities≤0.5%
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0.36%
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Total impurities≤1.0%
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0.52%
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Assay
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98.5~101.0%
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99.48%
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Conclusion
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Passed
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Our advantages:
1. High quality products with competitive prices.
2. We provide professional service.
3. Enough stock and Fast delivery.
4. We asure safe and effective shipping method.
Available tracking numbers to USA:
EE689150169CN
EE689150084CN
EE750056148CN
EE689151059CN
EA211716874HK
